Doc McStuffins, Spielzeugärztin
Kiara MuhammadDoc McStuffins (voice)
Jaden BettsDonny McStuffins (voice)
Kimberly BrooksSurfer Girl (voice), Dr. Maisha McStuffins (voice)
Gary Anthony WilliamsMarcus McStuffins (voice), Butch (voice)
Loretta DevineNurse Hallie (voice), Hattie (voice)
Robbie RistStuffy Filbert McStuffins (voice), Snowpeep (voice)
Lara Jill MillerHazel the Witch (voice), Mayella (voice), Lambie (voice), Snowpeep (voice)
Jess HarnellThe Wicked King (voice), Chilly (voice), The Dude / Rodriguez / Snowpeep (voice), The Wicked King / Buddy (voice)
Laraine NewmanProfessor Hootsburgh (voice), Southwest Sal / Snowpeep (voice), Aurora (voice), Trixie (voice), Trina Triceratops (voice), Southwest Sal (voice), Aurora / Professor Hootsburgh (voice)
Jeffrey Nicholas BrownBronty (voice), Otis / Tumbleweed (voice), Ben (voice)
Rob PaulsenSir Kirby (voice)
Grey DeLisleDress-Up Daisy (voice), Bouncy Babies (voice)
Deedee Magno HallSnuggs (voice)
Dee Bradley BakerSquibbles / Zane (voice), Robot Ray (voice), Squibbles (voice), Robot Ray / Stevie the Shark (voice)
Kari WahlgrenCeCe / Maya McStuffins (voice), Maya McStuffins (voice), Mrs. Sato / Suki (voice)
Mitchell WhitfieldOooey Gablooey (voice)- KKat FellerDixie (voice)
Ashley EdnerPandora (voice)
Cristina MiliziaLala (voice)
Jack ConleyDragon-Bot (voice)
Adam CroasdellWildlife Will (voice)
Tom KennyCharlie / Purple Monster (voice), Charlie (voice)
Michael GoughYul (voice), Officer Pete (voice)
Jeff FischerLenny (voice)
Rodger BumpassArmy Al (voice)
Dawnn LewisGrandma McStuffins (voice)
Lori AlanGloria Gorilla (voice), Gloria (voice)
Kylee AndersonEmmie (voice)
David KaufmanWilbur (voice), Sproingo Boingo (voice)
China Anne McClainTisha McStuffins (voice)
Peter MacNicolEgghead (voice)
Kath SoucieCeleste (voice)
Kyla KenedyTamara (voice)
Wayne KnightViewy Stewie (voice)
Audra McDonaldItty Bitty Bess (voice)
Julianne BuescherBella (voice)- DDamienne MerlinaFlora (voice)
Derek PhillipsWyatt (voice)- JJamie Sara LewisCalamity / Cheyenne (voice)
- ZZoe PessinEmmie (voice)
Michelle CampbellSadie (voice)
Maeve HigginsGillian (voice)
Eric Morgan StuartFlicker (voice)
Nika FuttermanRosie (voice)
Molly RingwaldDarla (voice)
G.K. BowesMelinda (voice)
Mary FaberKaraoke Katie (voice)
Lucinda ClareQueen Amina (voice)
LudacrisGus (voice)- JJohn Madison TyeTroy Triceratops / Perry's Dad (voice)
Yvette Nicole BrownTracy Triceratops (voice)- DDonovan WilliamsPerry (voice)
James Arnold TaylorBoppy (voice)
Jay GragnaniWill (voice)
Brady TuttonLittle Jack (voice)
Ty BurrellBig Jack (voice)
Ian GomezRicardo Racecar (voice)
Buddy KeatonLuca (voice)
Amber HoodSusie Sunshine (voice)- EElan GarfiasCarlos (voice)
John Michael HigginsZero (voice)
Stephen StantonGustov (voice)
Tiffany ThorntonXyla (voice)
Caitlin CarmichaelAlma (voice)
Steve BlumCommander Crush (voice)
Tony HaleTobias (voice)
Jeffrey TamborSanta Claus (voice)
Hynden WalchBubble Monkey (voice)
Sam RiegelOrville (voice)
Teo BrionesCarlos (voice)
Mick WingertStuart the Shark (voice)
Vanessa WilliamsDelilah the Nesting Doll (voice)
Jason MarsdenTeddy B. (voice)